Antihistamines, diuretics and drugs used to prevent and treat spasms, nausea and diarrhea often cause dry mouth, according to WebMD. Calcium-channel blockers and beta-blockers used to treat high blood pressure and heart disease list dry mouth as a possible side effect. Certain chemotherapy drugs also reduce saliva production. Oral tissue can become inflamed in the absence of sufficient saliva, leading to increased risk for gum disease or infections in the mouth. Xerostomia often leads to difficulty swallowing, loss of ability to taste, mouth pain and increased risk of cavities, reports the National Center for Biotechnology Information.
Sources: webmd.com, ncbi.nlm.nih.gov