In a lifetime, the body produces countless of substances that aid in its proper functioning. One of them is creatine which plays an important role in providing the key components of ATP or adenosine triphosphate. ATP fuels cell, tissue, and muscle functioning, so the human body needs 2-2.5 grams of creatine a day in order to support optimum functioning of all the body systems. Creatinine kinase, an enzyme which regulates breakdown of nutrients is found in skeletal muscles. The presence of CK can determine the occurrence of muscular damage. Its waste product is called creatinine, which indicates proper metabolism in the muscle if detected within normal range through a serum creatinine test.
An elevated serum creatinine level signals a kidney problem. Bear in mind that the kidneys are the body’s natural filters and those two bean-shaped organs are primarily responsible for eliminating wastes from the body. Since creatinine is a waste product of metabolism, it should be eliminated from the body through urine, not end up in the bloodstream. Therefore, high levels of creatinine in the blood indicate that the kidney don’t filter the blood well enough to excrete the substance through urine.
Elevated serum creatinine is a symptom of the following conditions: congestive heart failure, acute tubular necrosis or tissue death, glomerulonephritis or inflammation of the Glomeruli, severe dehydration, hypovolemic and cardiogenic shock, renal ischemia or blood deficiency to the kidneys, acute nephritic syndrome, and chronic renal failure. It can also indicate acute bilateral obstructive uropathy, end-stage renal disease, and Wilm’s tumor.
Serum creatinine in high levels pinpoints to these conditions, and along with them are symptoms that come with such conditions and diseases. Decreased urinary output, hypertensive crisis, hypotension, acute flank pain, and fever are just some of the most common symptoms that result from increased serum creatinine.
That’s why it is very important to seek proper medical consultation when you experience one or more of these symptoms. To your health and well being.